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Cytotoxicity of halogenomethylphenyl sulfones on Vero Cell Line ATCC CCL-81 in vitro Legend: Cytotoxicity of selected sulfones; red line points out 50% reduction of cell viability compared to growth control (50% cytotoxic concentration, CC 50 ). After 18 h of incubation, measurements were made using a spectrophotometer at 475 nm and 660 nm. The cytotoxicity was calculated using the formula: %cytotoxicity = (SA test sample–SA positive control)/ (SA negative control–SA positive control) × 100%; SA (specific absorbance) = A 475 (test)–A 475 (blank)–A 660 (blank). Data were presented as mean ± SD for free independent experiments

Journal: Mycopathologia

Article Title: Ergosterol-Dependent Membrane Stress and Calcineurin- HSP90 Signaling Govern Fluorinated Sulfone-Induced Cell Death in Candida albicans

doi: 10.1007/s11046-026-01081-6

Figure Lengend Snippet: Cytotoxicity of halogenomethylphenyl sulfones on Vero Cell Line ATCC CCL-81 in vitro Legend: Cytotoxicity of selected sulfones; red line points out 50% reduction of cell viability compared to growth control (50% cytotoxic concentration, CC 50 ). After 18 h of incubation, measurements were made using a spectrophotometer at 475 nm and 660 nm. The cytotoxicity was calculated using the formula: %cytotoxicity = (SA test sample–SA positive control)/ (SA negative control–SA positive control) × 100%; SA (specific absorbance) = A 475 (test)–A 475 (blank)–A 660 (blank). Data were presented as mean ± SD for free independent experiments

Article Snippet: Fig. 1 Cytotoxicity of halogenomethylphenyl sulfones on Vero Cell Line ATCC CCL-81 in vitro Legend: Cytotoxicity of selected sulfones; red line points out 50% reduction of cell viability compared to growth control (50% cytotoxic concentration, CC 50 ).

Techniques: In Vitro, Control, Concentration Assay, Incubation, Spectrophotometry, Positive Control, Negative Control